The Proteintech Blog

Category Archives: Antibody case studies

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AMPA Receptor Trafficking Shapes the Synapse

admin October 23, 2013

  By Simon Hackett Retinal ganglion cells (RGCs) are neurons located near the ganglionic cell layer of the retina. These cells receive impulses from photoreceptor cells via bipolar and amacrine cells mediated by AMPA-class glutamate receptors (AMPA receptors). Two types of these receptors exist: receptors lacking GluA2 subunits, permeable to calcium ions, and those with a… Continue Reading »

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COMT antibody focus: Urinary exosomes used to identify novel kidney proteins

admin July 2, 2013

Proteintech’s rabbit polyclonal Catechol O-methyltransferase (COMT) antibody features in new research published in the Journal of Proteomics. All epithelial cells are now known to produce exosomes, and renal epithelial cells – including podocytes and the tubular epithelium – are no exception. Moreover, the urinary exosomes they release could be of great pathophysiological importance as they… Continue Reading »

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MEF2C Antibody Features in Nature Biotechnology

admin February 26, 2013

Myocyte-specific enhancer factor 2, encoded by the MEF2C gene, is a well-established transcription factor involved in skeletal, cardiac and smooth muscle cell development. More recently, its role in brain development and function has also entered the research spotlight; the importance of MEF2C has been demonstrated in neural stem cells (NSCs), and by the observation of… Continue Reading »

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MTAP-ing into mesothelioma diagnostics

admin May 8, 2012

Proteintech’s anti-MTAP antibody (11475-1-AP) has appeared in several research papers detailing the potential diagnostic value of the methylthioadenosine phosphorylase (MTAP) protein. The latest paper to feature our MTAP antibody was published in Histopathology this month and describes the diagnostic value of detecting MTAP in a subset of mesothelioma. Malignant pleural mesothelioma (MPM) is an aggressive… Continue Reading »

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