The Proteintech Blog

cancer research

Scanning electron micrograph of a human T-cell (Source: Wikimedia Commons, Original Source: NIH/NIAID.)
General News, News
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PD-1 Blockade: Priming the Immune System to Combat Cancer

admin April 19, 2013

  The immune system’s role in cancer was a recurring topic at this year’s American Association of Cancer Research (AACR) Annual Meeting. From the outset of the conference, talks and poster presentations detailing how the immune response can be primed to combat cancer seemed ubiquitous; a reflection of the progress made in the field of… Continue Reading »

DNA Repair. Source: Wikimedia Commons.
Antibody, Focus article, Guest blog
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NEIL3 Antibody Used to Investigate Mechanisms of DNA Repair

admin April 2, 2013

  Guest post by Katie Griffiths Base excision repair is a crucial mechanism involved in DNA repair and protection. The process is initiated by DNA glycosylases, which recognize and cleave damaged or incorrectly paired bases. Owing to the importance of this process, considerable study has gone into understanding the cellular and molecular mechanisms involved, and… Continue Reading »

See you in Washington D.C for the 2013 installment of the Annual AACR Meeting
Proteintech News
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What to See at The AACR Annual Meeting 2013 | Proteintech’s Top Picks

Deborah March 26, 2013

The last installment of the AACR Annual Meeting saw Proteintech celebrate its 10 year anniversary, its blog cover several conference sessions and interview prominent thought leaders in the field of cancer research. Whilst celebrations of Proteintech’s eleventh year of providing quality antibodies will be significantly more low-key, its resident blogger (yours truly) is looking forward… Continue Reading »

Immunohistochemical staining of paraffin-embedded human lung cancer using KEAP1 Antibody 10503-2-AP (10x lens).
Focus article, Guest blog, Product focus
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NSCLC Research: Anti-Keap1 Antibody Helps Uncover Target’s Biomarker Potential

admin March 6, 2013

Guest post by Katie Griffiths Kelch-like ECH-associated protein 1 (Keap1) is a crucial substrate adapter protein for the Cul3-RBX E3 ubiquitin ligase complex, and a key regulator of the Nrf2 cytoprotective pathway. Under normal conditions, levels of Nrf2 are constantly regulated by rapid ubiquitination and proteasomal degradation; thus the antioxidant response is continually suppressed. However,… Continue Reading »

typing
Events, Guest blog, Uncategorized
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Are you attending the AACR Annual Meeting this year?

admin January 29, 2013

(And want to earn a little extra spending money?) Do you have a blog or just a natural flare for writing? Do you want to cover the latest topics in cancer research? …If the answer to these questions is “YES!” then we would like to hear from you! Proteintech not only provides the cancer research community with… Continue Reading »

IHC of paraffin-embedded cervical cancer using MMP-1 antibody 10371-2-AP (as viewed under 40x lens).
Antibody, Focus article
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Matrix Metalloproteinase Antibodies

admin March 6, 2012

The study of matrix metalloproteinases (MMPs) is highly relevant to cancer research, particularly in the area of metastasis. Secreted into the extracellular matrix (ECM), these zinc-dependent endopeptidases are capable of degrading many kinds of ECM protein and facilitating invasion and migration. Conversely they can also inhibit metastasis in certain scenarios. Proteintech has a collection of… Continue Reading »

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